Deciphering the protein motion of S1 subunit in SARS-CoV-2 spike glycoprotein through integrated computational methods
نویسندگان
چکیده
منابع مشابه
Antimyogenic Effect of SARS-CoV Spike Protein in C2C12 Myoblasts
C2C12 myoblasts serve as well-established model system to study myogenesis, as they fuse to form multinucleated myotubes. Severe acute respiratory syndrome coronavirus (SARS–CoV) spike (S) protein plays a crucial role in viral entry. Exogenous expression of S protein in C2C12 myoblasts inhibits the formation of myotubes. Global changes in gene expression were studied in C2C12 cells expressing S...
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In the face of the worldwide threat of severe acute respiratory syndrome (SARS) to human life, some of the most urgent challenges are to develop fast and accurate analytical methods for early diagnosis of this disease as well as to create a safe anti-viral vaccine for prevention. To these ends, we investigated the antigenicity of the spike protein (S protein), a major structural protein in the ...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Structure and Dynamics
سال: 2020
ISSN: 0739-1102,1538-0254
DOI: 10.1080/07391102.2020.1802338